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Scioto Brush Creek State Nature Preserve protects over a mile of Scioto Brush Creek which is one of the most biologically diverse streams in Ohio. Scioto Brush Creek has over 70 species of fish including longnose gar (Lepisosteus osseus) and rosyside dace (Clinostomus funduloides). The preserve contains mature trees, spring wildflowers, and rare species. The preserve protects one of four populations of the Federal Threatened Appalachian spiraea (Spiraea virginiana), a shrub known only in Ohio from the Scioto Brush Creek watershed.